United States

1,580 Articles

Designing AI-Engineered Enzymatic Proteins to Break Down Proteins Linked to Neurological Diseases

Artificial intelligence

Designing AI-Engineered Enzymatic Proteins to Break Down Proteins Linked to Neurological Diseases

Researchers from David Baker’s team at the University of Washington used AI protein-design tools to build proteases capable of cleaving specific protein sequences, including targets associated with Alzheimer’s disease and frontotemporal dementia. The designs showed measurable activity and major improvements after the introduction of optimized mutations, but they remain less efficient than natural enzymes and face significant obstacles before any therapeutic use.

2026-10-14

Chainguard Launches Harness to Discover Vulnerabilities and Safely Complete the Work of Coding Agents

Cybersecurity

Chainguard Launches Harness to Discover Vulnerabilities and Safely Complete the Work of Coding Agents

Chainguard has launched the Harness platform, which uses advanced artificial intelligence models to discover exploitable vulnerabilities that traditional scanning tools may miss, alongside isolated microVM environments and the execution of CI checks within coding agents’ workflows. The launch comes with survey results indicating that 66% of companies with more than $1 billion in revenue sometimes leave high or critical vulnerabilities unpatched.

2026-10-14